Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and

Fibrosis

An interpretation of the lung transition accompanying the onset of COPD from one
marked by normal lung stem cells (blue petals) to one dominated by pathogenic variant
stem cells (yellow, red, and green). The Middle Ages motif along the bottom reflects
the enormity and abject state of the disease, and the hummingbird motifs are hope.
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Final Image

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Sketch

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Line Drawing

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Client: Houston University Frank Biology and Biochemistry Lab